When it comes to HIV protection, no! All types of daily PrEP are equally effective, whether they are brand names or generic versions. A generic version of a medication, like Truvada, contains the same drugs in the same amount.
Types of PrEP differ when it comes to price. Generic medications are cheaper, and there are multiple generic versions of Truvada available. These are covered by provincial drug plans, which means you can get them for free or at low cost. Truvada and Descovy are not covered by provincial drug plans. If you are paying out of pocket they are more expensive, but they can be covered by private insurance.
Types of PrEP can also differ when it comes to side effects. Descovy has a lower risk of kidney side effects compared to Truvada and generic versions. If you are at risk of these or experiencing them, then Descovy could be a good option for you.